Twirla 
stickswith you*
Meet Twirla
The weekly birth control you wear
Twirla (levonorgestrel/ethinyl estradiol) is a low dose†, once-weekly patch for women with Body Mass Index (BMI) less than 30 kg/m2 who can become pregnant.
†
30 mcg/day ethinyl estradiol
Twirla Sticks With You
Whether you’re working out or working at your desk, Twirla is designed to stick with you and proven to stay in place.*
* In a year-long study, about 5% of 55,900 patches detached completely, especially with water exposure. Patches adhered best on the abdomen.
To help it adhere, limit water exposure and avoid excess lotions or oil. Check daily for detachment.
Why Twirla?
Stick with what works for you
Your birth control isn’t just another decision – it’s your chance to take charge of your reproductive health.
No daily pills
No invasive procedures
No implanted devices
in your body
Compare Your Options
Is Twirla the right
choice for you?
Talk to your healthcare provider about your options.
Here are some factors to take into consideration:
| Contraceptive | Frequency | Application | Hormones |
|---|---|---|---|
| Pill | Daily | At home | Progestin only or
Progestin + Estrogen |
| Twirla | Weekly | At home | Progestin + Estrogen |
| Ring | Monthly | At home | Progestin + Estrogen |
| Shot | 3 months | In office | Progestin only |
| Implant | 3 years | In office | Progestin only |
| IUD | 3 - 10 years | In office | Non-hormonal or Progestion only |
Save on Twirla
Eligible patients may save on Twirla
As a Twirla patient, you may be eligible to pay as little as $25 per 1– or 3–month prescription fill (a 3 month fill may cost patients $8.33 per month).
No activation needed: Simply ask your pharmacist to apply the savings to your prescription using the information provided via texting TWIRLA to 31700‡ or downloading the Copay Card§.
‡
Maximum savings limits apply; patient out-of-pocket expense will vary depending on insurance coverage. Offer not valid for patients enrolled in Medicare, Medicaid, or other federal or state healthcare programs. Please see Twirla copay card for Program Terms, Conditions, and Eligibility Criteria.
§
Message/data rates may apply. Message frequency varies. You may opt out of receiving texts at any time by texting STOP.
Frequently Asked Questions
Sticking to the basics
What is Twirla?1
Twirla is a birth control patch for women with a BMI less than 30 kg/m2 who can become pregnant. It contains two female hormones, a progestin called levonorgestrel, and an estrogen called ethinyl estradiol. Birth control methods that have both an estrogen and a progestin are called combination hormonal contraceptives (CHCs).
Twirla is less effective in women with a BMI of 25 kg/m2 or more.
Twirla does not protect against HIV infection (AIDS) and other sexually transmitted infections (STIs).
How well does Twirla work?1
Your chance of getting pregnant depends on how well you follow the directions for using TWIRLA. The better you follow the directions, the less chance you have of getting pregnant.
For TWIRLA to be most effective, you must use TWIRLA exactly as your healthcare provider tells you to. Each patch must be fully attached to the skin during the 7 days in order for it to work the best.
TWIRLA is less effective in women who have a BMI of 25 kg/m2 or more. If you have a BMI of 30 kg/m2 or more, talk to your healthcare provider about other methods of birth control which may be right for you.
Who should not use Twirla?1
Do not use Twirla if you:
- smoke and are over 35 years old.
- have or have had blood clots in your arms, legs, eyes or lungs.
- have had a stroke.
- have had a heart attack.
- have certain heart valve problems or heart rhythm problems that can cause blood clots to form in the heart.
- have a problem that makes your blood clot more than normal that you were born with (inherited) or that has happened for other reasons such as medicines, surgery or injuries (acquired).
- have high blood pressure that is not controlled.
- have diabetes and you are over the age of 35, have high blood pressure or have kidney, eye, nerve, or blood vessel damage, or have had diabetes for more than 20 years.
- have had certain kinds of severe migraine headaches with aura, numbness, weakness or changes in vision, or have any migraine headaches if you are over age 35.
- have a BMI of 30 kg/m2 or more.
- have liver problems including liver tumors, hepatitis, cirrhosis, or liver disease.
- have unexplained vaginal bleeding.
- are pregnant or think you may be pregnant. However, TWIRLA is not known to cause birth defects when used by accident during pregnancy.
- have had breast cancer or any cancer that is sensitive to female hormones.
- are allergic to any of the ingredients in TWIRLA. See a complete list of ingredients at the end of this Patient Information leaflet. Symptoms of an allergic reaction you may include itching and irritation at the patch site.
- take any Hepatitis C drug combination containing ombitasvir, paritaprevir, ritonavir, with or without dasabuvir. This may increase levels of a liver enzyme called alanine aminotransferase (ALT) in the blood. TWIRLA may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy (also called cholestasis of pregnancy) or related to previous use of hormonal birth control. Tell your healthcare provider if you have ever had any of the above conditions. Your healthcare provider may recommend another method of birth control.
TWIRLA may not be a good choice for you if you have ever had jaundice (yellowing of the skin or eyes) caused by pregnancy (also called cholestasis of pregnancy) or related to previous use of hormonal birth control.
Tell your healthcare provider if you have ever had any of the above conditions. Your healthcare provider may recommend another method of birth control.
What are the most common side effects on Twirla?1
The most common side effects of TWIRLA include:
- skin reactions at the patch site such as bumps, redness or changes in color of your skin, bleeding itching, rash, dryness, pain and swelling
- nausea
- headache
- menstrual cramps
- weight gain
These are not all the possible side effects of TWIRLA.
Talk to your healthcare provider for medical advice about side effects.
You may report side effects to FDA at 1-800-FDA-1088.